以下为句子列表：
英文: Aware of the importance of extracellular matrix, tissue engineers have long sought an ideal substitute to serve as a platform for growing living tissues.
中文: 组织工程学家了解到细胞外间质的重要性后，就一直在找寻一种理想的替代品，以做为活体组织生长的基台。
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英文: Being a kind of adhesion molecules associating cells with extracellular matrix, integrins play a variety of roles in the process of invasion and metastasis in pancreatic adenocarcinoma.
中文: 胰腺癌手术切除率低死亡率高的重要原因之一是肿瘤早期即能发生局部浸润和远处器官转移，整合素作为细胞与细胞外基质的黏附分子，在胰腺癌侵袭及转移过程中发挥多重作用。
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英文: But after the cells have established themselves and begun secreting their own extracellular matrix, the scaffold should dissolve, leaving behind only healthy tissue.
中文: 然而当细胞定居下来，并开始分泌自己的细胞外间质时，这些支架也会溶解，仅留下健康的组织。
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英文: Cascades are important in signaling pathways, there extracellular signals(such as hormones or ions) bind with receptors on the cell membrane, triggering changes in membrane proteins that activate proteins on the cytoplasmic side of the emmbrane, setting o
中文: 在信号传导通路上级联反应起着重要的作用，细胞外的信号（激素，离子等）和细胞膜上的受体结合，引起膜蛋白的变构，进而和细胞膜上靠近细胞质的蛋白结合，引发一系列的反应。
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英文: 2. Exogenous ceramide can in certain extent increase the cell's free Ca2+ as well as induce the NIH 3T3 cell apoptosis, increased was mainly come from the extracellular cadium initiated by cadium exhausting.
中文: 2.外源性神经酰胺在一定的剂量范围内可以导致NIH3T3细胞的凋亡和细胞内游离钙的升高并且有一定的剂量依赖性关系,这说明Ca~(2+)参与了凋亡信号的传递; 胞内游离钙的增加主要来源于钙池耗竭引发的外Ca~(2+)内流;
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