以下为句子列表：
英文: The idea of using Botox as a preventative agent for migraines came in 1992 when a Los Angeles plastic surgeon noticed fewer headaches in a patient who was being treated with the agent for its skin-smoothing effects.
中文: 使用肉毒杆菌毒素作为偏头痛预防药物的构想，始自洛杉矶一位整形外科医师在1992年时注意到，一名患者原本是为了让肌肤平滑而接受这种药剂治疗时，头痛次数减少了。
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