详细解释:
探讨意识指数(Index of Consciousness,IOC)与脑电双频指数(Bispectral Index, BIS)相比,靶控丙泊酚全麻诱导时用于监测镇静深度的相关性。方法 研究纳入行普外或妇科手术的患者30例,靶控丙泊酚全麻诱导期间,同时监测IOC和BIS。记录镇静评分(observers assessment of alertness/sedation scale, OAA/S)由5分逐级降低至1分时,每次OAA/S 评分即刻的IOC及BIS值,以及相应点的丙泊酚效应室浓度。结果 IOC、BIS与OAA/S的相关系数r分别为0.988和0.986(P<0.001),BIS与IOC的相关系数r为0.997(P<0.001)。结论 IOC用于靶控丙泊酚全麻诱导时的镇静深度监测,与BIS具有良好的相关性。 Objective To compare a new level of consciousness monitor, called the index of consciousness (IOC) with the bispectral index (BIS) during propofol target-controlled infusion (TCI) anaesthesia induction. Methods After ethical committee approval and written patient consent, data from 30 patients were recorded. All patients were induced with propofol target-controlled infusion (TCI), until the Observer’s Assessment of Alertness and Sedation (OAAS) scale level 1 was reached, and then IOC and BIS were calculated during OAAS 5~1. Results IOC (0.988, P<0.001) and BIS (0.986, P<0.001) positively correlated with OAAS, while IOC positively correlated with BIS (0.997, P<0.001). Conclusions IOC has the good correlation with BIS during propofol target-controlled infusion (TCI) anaesthesia induction.
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