以下为句子列表：
英文: To improve the performance of assays on the oligonucleotide microarray, the factors that influence the hybridization effects such as surface chemistry, probe size, spacer length, hybridization conditions etc were intensely studied and optimized.
中文: 为改善寡核苷酸芯片的分析性能，对影响芯片杂交结果的因素，如片基表面的化学处理、探针的长度、间隔臂的长度、杂交条件等，进行了深入的研究和优化。
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英文: The principle of antisense therapy is transferring the sequence-specific binding of an antisense oligonucleotide to target DNA or mRNA, and sele.
中文: 反义治疗(antisense therapy)就是在体外合成一段能与目的基因DNA或RNA互补的小分子的寡核苷酸片段,转入靶细胞,选择性地关闭或抑制致病基因的表达,从而起到防治疾病作用的一种治疗方法。
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英文: Locked nucleic acid (LNA) is a novel oligonucleotide analogue in which 2 O and 4 C positions in the b D ribofuranosyl ring are joined via an O methylene, S methylene or amino methylene moiety, locked in a C3 endol 3E north (N) type furanose conformation.
中文: 锁核酸 (lockednucleicacid ,LNA)是一种新型的寡核酸衍生物 ,结构中 β D 呋喃核糖的 2’ O ,4’ C位通过缩水作用形成环形的氧亚甲基桥、硫亚甲基桥或胺亚甲基桥 ,呋喃糖的结构锁定在C3’内型的N构型 ,形成了刚性的缩合结构。
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英文: Chk/ protein expression was investigated by Western blot and confocal micros copy in best condition of transfection of antisense oligonucleotide targeting Ch k/ by lipofection.
中文: 以脂质体作为载体 ,转染Chk 反义寡核苷酸于K 细胞 ,用Westernblot和共聚焦显微镜检测转染Chk 反义寡核苷酸后Chk 蛋白表达 ;
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英文: EFFECT OF ANTISENSE OLIGONUCLEOTIDE AGAINST hTR RNA ON THE TELOMERASE ACTIVITY AND APOPTOSIS IN K562 CELLS
中文: hTR基因反义核酸对K562细胞端粒酶活性和凋亡的影响
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