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ED-71 improved the expression of P27kip1.ConclusionED-71 treatment could inhibit proliferation of human liver carcinoma cell HepG2,cause partial differentiation and induce the expression of P27kip1.
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结论ED-71抑制人肝癌细胞株HepG2的生长,诱导人肝癌细胞分化,使细胞阻滞于G1期,可能与ED-71诱导人肝癌细胞中抑癌基因P27kip1蛋白的表达有关。 |
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EDITORIAL BOARD OF CHINESE JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
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中国临床药理学与治疗学杂志第三届编委会 |
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EFFECT OF 1α, 25-DIHYDROXY-VITAMIN D_3 ON DIFFERENTIATION AND PROLIFERATION OF A HUMAN MYELOID LEUKEMIA CELL LINE
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1α,25二羟基维生素D_3对人早幼粒白血病细胞(HL—60)的诱导分化作用 |
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EFFECT OF A HUMAN FETAL LIVER FACTOR IN SUPPRESSION OF HL-60 CELL GROWTH IN VITRO
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胎儿肝脏中一种抑制HL-60细胞生长的因子初步研究 |
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EFFECT OF ACELL DIFFERENTIATION INDUCER,GANGLIOSIDE GM3,ON THE CELL MEMBRANE FLUIDITY OF A HUMAN PROMYELOCYIC CELL LINE HL-60
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GM_3对HL-60细胞的诱导分化作用及细胞膜流动性的影响 |
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EFFECT OF ANTISENSE OLIGONUCLEOTIDE AGAINST hTR RNA ON THE TELOMERASE ACTIVITY AND APOPTOSIS IN K562 CELLS
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hTR基因反义核酸对K562细胞端粒酶活性和凋亡的影响 |
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EFFECT OF CALCIUM SALT ON THE PHARMACOKINETICS OF NORFLOXACIN IN RABBITS
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家兔体内钙盐对诺氟沙星药动学的影响 |
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EFFECT OF CALCULATION CELL SIZE ON RESULTS OF MOLECULAR DYNAMICS SIMULATION
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分子动力学模拟中计算元胞尺寸对计算结果的影响 |
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EFFECT OF CYTOKINES ON PMSG-hCG INDUCED OVULATION BY IMMATURE FEMALE MICE
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细胞因子对PMSG-hCG诱发未成年小鼠排卵的影响 |
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EFFECT OF CYTOKINES ON THE PROLIFERATION OF ADULT MURINE CD4 CD8 THYMOCYTES
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几种细胞因子对成年小鼠CD4~-CD8~-胸腺细胞的增殖作用 |
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EFFECT OF DANAZOL ON THE LIVER AND IMMUNE ORGANS
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炔睾醇对肝脏及免疫器官的作用 |