以下为句子列表:
英文: Levetiracetam (Lev) is a novel orally active antiepileptic drug, structurally unrelated to other antiepileptics and with an entirely unique preclinical profile.
中文: 摘要左乙拉西坦是一种新型的口服抗癫痫药物,与其他抗癫痫药物的结构不同,具有全新的抗癫痫机制。
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英文: Prophylactic use of antiepileptic drugs is not recommended, and potential interactions between antiepileptic and chemotherapeutic agents persuades against the use of enzyme-inducing antiepileptic drugs.
中文: 抗癫痫病的药物与化疗剂之间存在潜在的交互作用,不推荐预防性使用抗癫痫病的药物。
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英文: The antiepileptic activity of Lev was assessed in a number of animal models ereated for investigation of epileptic seizures.
中文: 多种动物模型显示左乙拉西坦具有抗癫痫特性。
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英文: The pharmacokinetic profile of Lev closely approximates the ideal characteristics expected of an antiepileptic drug, with good bioavailability, linear and time-invariant kinetics, minimal protein binding, and least metabolism.
中文: 左乙拉西坦几乎具备了较好的抗癫痫药物的所有药动学特性:生物利用度高、线性曲线、低蛋白结合率、无肝酶诱导作用。
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英文: The precise mechanisms of its antiepileptic effect is unknown and does not appear to derive from any ion passage interaction with known mechanisms involved in inhibitory and excitable neurotransmission.
中文: 左乙拉西坦的确切抗癫痫机制尚不明,但与传统抗癫痫药物作用于离子通道或兴奋性、抑制性神经递质系统不同。
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