以下为句子列表：
英文: 120 patients with CHB and phenotypic lamivudine resistance defined as detectable HBV DNA and elevated ALT levels were enrolled in an observational, retrospective, multicenter study performed in Spain.
中文: 对拉米夫定耐药的慢性乙肝患者面临着病情恶化甚至死亡的危险。本文的目的就是研究阿德福伟在对拉米夫定耐药的慢性乙肝患者当中使用的安全性和有效性。
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英文: A 59-year-old man receiving long-term lamivudine therapy experienced a fatal exacerbation of hepatitis B virus (HBV) infection resulting in hepatic necrosis following the emergence of variant HBV.
中文: 一例长期使用拉米夫定治疗的59岁男性患者在HBV变异株出现后乙肝病毒感染发生致命性加重，导致肝坏死。
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英文: As one patient showed a relapse, a total of eight (31%) patients responded to lamivudine pulse therapy over a mean period of 17.3 ± 4.5 months.
中文: 一名患者病情反跳,8名(31.%)患者对拉米脉冲疗法,在17.3±4.5月份平均值时间内有效应.
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英文: Combination of lamivudine and interferon deserves further assessment.
中文: 拉米夫啶和干扰素联合治疗值得进一步研究。
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英文: Combination of lamivudine with other antiviral agents or immune modulators is likely to be more effective.
中文: 拉米夫啶和其他抗病毒药物或免疫调节剂联合使用看起来似乎更有效。
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