以下为句子列表：
英文: No amino acid substitutions known to confer adefovir resistance were detected in these patients.
中文: 没有已知的，会造成阿德福韦抗药氨基酸替代物质在这些患者中发现。
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英文: The objective of this study was to assess the efficacy and safety of adefovir dipivoxil/ ADV (Hepsera) therapy under compassionate use in patients with chronic hepatitis B (CHB) and lamivudine resistance.
中文: 本文的目的就是研究阿德福伟在对拉米夫定耐药的慢性乙肝患者当中使用的安全性和有效性。
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英文: AIM:To investigate the pharmacokinetics of adefovir dipivoxil (ADV) with a single and multiple-dose oral administration in Chinese healthy volunteers.
中文: 目的：评估健康志愿者单次、多次口服阿德福韦酯片剂(ADV)的药动学。
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