以下为句子列表：
英文: Abstract: Aim To synthesize isonucleoside-incorporated oligonucleotides and investigate their binding abilities with complementary sequences.Methods The synthesis was performed on DNA synthesizer, and the binding behavior was investigated by thermal denat
中文: 文摘:目的合成异核苷掺入寡核苷酸并考察它们与互补序列的结合能力.方法采用DNA固相合成仪合成寡核苷酸,通过热变性实验考察双链的稳定性.结果合成了四条单异核苷掺入的寡核苷酸,热变性实验结果发现异核苷的引入降低了双链的稳定性,当异核苷处于寡核苷酸链的中央时,这种影响更为明显.异核苷6′-OH处于游离和烯丙基保护状态时的结果没有显著差异.结论寡核苷酸中的异核苷使链发生扭曲,从而导致双链稳定性降低.
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英文: Iron oxide magnetic nanoparticles with biocompatibility and functional coatings via appropriate surface chemistry approaches have been used for immobilization of cells, proteins, enzymes, antibodies, oligonucleotides and drugs through covalent bonding or
中文: 摘要氧化铁磁性纳米粒子通过表面化学修饰得到无机、有机或聚合物壳包覆在其表面。
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英文: >[Objective] To study the inhibitory effect of bcl-2 antisense oligonucleotide(ASODN)combined with radiation on lung carcinoma cells NCI-H446.
中文: [目的]研究Bcl-2反义寡核苷酸联合照射对肺癌细胞的抑制作用。
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英文: Experimental Studies of the Effect on Tumor Neovascularization after TACE on Rabbit VX2 Liver Neoplasms by HIF-1α Antisense Oligonucleotides Loaded Nanoparticles;
中文: 1992年缺氧诱导因子-1(hypoxia-inducible factor-1，HIF-1α)的发现使得调控缺氧诱导基因成为一种新的治疗热点。
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英文: Locked nucleic acid (LNA) is a novel oligonucleotide analogue in which 2 O and 4 C positions in the b D ribofuranosyl ring are joined via an O methylene, S methylene or amino methylene moiety, locked in a C3 endol 3E north (N) type furanose conformation.
中文: 锁核酸 (lockednucleicacid ,LNA)是一种新型的寡核酸衍生物 ,结构中 β D 呋喃核糖的 2’ O ,4’ C位通过缩水作用形成环形的氧亚甲基桥、硫亚甲基桥或胺亚甲基桥 ,呋喃糖的结构锁定在C3’内型的N构型 ,形成了刚性的缩合结构。
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