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activation

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英文: Conclusion The inactivation of suppressor gene p16 or low expression of protein p16 was associated with the progression,the degree of cell differentiation and neck metastasis in NPC,but it was not associated with the size of primary foci.

中文: 结论抑癌基因p16失活或p16蛋白低表达可能与鼻咽癌的发生、癌细胞的分化程度及颈淋巴结转移有关,而与鼻咽癌原发灶大小无关。        更详细...
英文: Effects of salvianolic acid- B on TGF-β1 stimulated hepatic stellate cell activation and its intracellular signaling

中文: 丹酚酸B盐对转化生长因子-β1刺激肝星状细胞活化与胞内信号转导的作用        更详细...
英文: Excess activation of Th2 cells evokes Th2 immune response, and it causes elevated Th2 cytokines. Th2 cytokines such as IL-4, IL-5 and IL-13 play a pivotal role on the onset and maintenance of airway allergic inflammation in asthma.

中文: “Th1/Th2偏移”假说被认为是哮喘发病的主要免疫学机制,该假说认为Th2细胞的过度活化导致了Th2反应为主的免疫反应,Th2型细胞因子IL-4、IL-5、IL-13等分泌增多在哮喘的气道炎症发生发展中起关键作用[3-5]。        更详细...
英文: In addition to strong IFN-γ inducing activity, IL-18 is able to induce production of Th1 cytokines such as GM-CSF, IL-2 and TNF-α to promote proliferation, development and differentiation of Th1 and activation of NK.

中文: 除诱导细胞产生IFN-γ外,IL-18还能诱导GM-CSF,IL-2及TNF-α等其他Th1型细胞因子的产生,具有促进Th1细胞发育、增殖和分化以及增强NK细胞活性产生抗肿瘤作用。        更详细...
英文: and upregulate FasL expression on the cell surface of NK92.Conclusion:Preactivation of TM-TNF-α reverse signaling may potentiate NK-mediated cytotoxicity by promoting exocytosis, secretion of sTNF-α and FasL expression.

中文: 结论TM-TNF-α反向信号可能通过促进NK92细胞胞吐、sTNF-α分泌及FasL的表达而促进NK92细胞对靶细胞的杀伤。        更详细...
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