以下为句子列表：
英文: Metformin, an antihyperglycemic agent used in type 2 diabetes, was also inestigated because it inhibits PTP opening in transformed cell lines.
中文: 二甲双胍是用于治疗2型糖尿病的降糖药,能够抑制转化细胞系PTP的开放,所以我们对其进行调查.
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英文: The hyperglycemic activity of pancreatic extracts was encountered some 80 yr ago during efforts to optimize methods for the purification of insulin.
中文: 约80年前，在尝试优化胰岛素提纯技术的过程中人们发现胰腺提取液能引起高糖状态。
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