Composition:Tech. grade is ≥94% pure.Form:Colourless crystals. M.p.: 51-52 ℃ B.p.: Decomposition begins at 160 ℃ V.p.: 0.22 mPa (50 ℃) (Antoine) Henry: 2.578 × 10-4 Pa m3 mol-1 (calc.)S.g./density: 1.348 at 25 ℃ Solubility: In water 4.2 mg/l (25 ℃). Readily soluble in most organic solvents, e.g. xylene, benzene, carbon tetrachloride, dichloromethane, trichloroethylene. In acetone, toluene, ethyl acetate >400, hexane 16.6 (all in g/l, 20 ℃).Stability: Hydrolysed by acids and alkalis. Unstable in undiluted form. F.p.: 34? ℃ (Abel-Pensky closed method)
毒 理 学 性 质
LD50/LC50
Oral: Acute oral LD50 for rats 151-778 mg/kg (depending on sex and carrier).Skin and eye Acute percutaneous LD50: for rats >2000 mg/kg. Non-irritating to skin; slightly irritating to eyes (rabbits). Inhalation: (4 h) for rats 1220 mg/m3 air.Birds: Acute oral LD50 for quail (depending on carrier and sex) 118-480 mg tech./kg. Dietary LC50 (14 d) for mallard duck c. 340, bobwhite quail c. 300 mg/kg.Fish: LC50 (96 h) for carp 2.8-6.1, rainbow trout 0.48-1.14, bluegill sunfish 0.28 mg/l.Bees: LD50 (24 h, contact) 0.25 μg/bee.Daphnia: LC50 (48 h) 0.36 μg/l (soft water); 0.63 μg/l (hard water). NOEL 0.18 μg/l in hard and soft water.Algae: LC50 (72 h) for Scenedesmus subspicatus 65.5 mg/l.Worms: LC50 (14 d) for Eisena foetida >1000 mg/kg soil.Other aquatic spp.:
NOEL
(2 y) for rats 5 mg/kg diet. A 3-generation test on rats showed no effect at 50 mg/kg diet.
NOAEL
LOAEL
ADI
(JMPR) 0.004 mg/kg b.w. [1992].
BMD
PTWI
PTDI
RfD
MTD
Acute RfD
是否致癌物
×
是否基因致癌物
×
其他毒理学性质
Toxicity class EPA(formulation): II
应 用 情 况
国内应用情况
国内登记或注册
×
国内生产
×
国外进口
×
国外应用情况
无
其 他 信 息
类别
Fungicide
作用
Biochemistry: Prevents development of appressoria by fungal conidia. Inhibits melanin biosynthesis in some species. Mode of action: Systemic fungicide with protective and curative action. Absorbed by the leaves and shoots, and translocated acropetally within the plant. Uses: Control of Erysiphe, Helminthosporium and Rhynchosporium in cereals, Podosphaera in pome fruit, Erysiphe and Sphaerotheca in cucurbits, Erysiphe in tomatoes, Oidium and Podosphaera in stone fruit, and Uncinula in grapes. Application rates vary from 100-600 g/ha, depending on crop. Phytotoxicity: Non-phytotoxic when used as recommended (except to some varieties of grape). Compatibility:
作用特点
无
代谢情况
Animals: Extensively metabolised and rapidly eliminated in rats, DT50 4-5 h. Excretion mainly in urine; the most important metabolite is ethyl 2-hydroxy-5-methyl-6-pyrazolo[1,5-a]pyrimidine-carboxylate, partly excreted as a sulfate conjugate. Plants: Half-life in wheat leaves c. 19 days. Following hydrolysis of the phosphate bond, a β-glucoside of the pyrazolopyrimidine is formed. Soil/environment: Soil degradation occurs by cleavage of the phosphoric acid group, saponification of the carboxylate fraction and further degradation of the heterocyclic ring system, ultimately to CO2. Degradation rates vary with soil type and properties, with no obvious correlation with any single soil characteristic. DT50 10-21 d, DT90 111-235 d (field). Strongly absorbed to soils (Koc 1332-2670, calc.). Column studies and leaching models indicate pyrazophos will not leach.
