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[Obejectives] A common pathogenetic mechenism of Alzheimer's disease (AD) and Creutzfelt-Jakob Disease (CJD) is the accumulation in the brain of abnormally folded proteins leading to neurodegeneration.
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老年性痴呆(Alzheimer's disease, AD)与Creutzfelt-Jakob病(CJD)同属于ND中的蛋白构象病,其发病是由于蛋白质异常折叠导致构象变化,正常可溶的蛋白质转化成不可溶的蛋白质聚合体,前者为β淀粉样蛋白(β-Amyloid, Aβ)沉积,后者为蛋白酶K抵抗的朊蛋白(Prion Protein, PrP~(SC))沉积。 |
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The senile dementia, also known as Alzheimer's disease(AD) is a kind of primary regressive diseases of nervous system among the elder.
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老年性痴呆(Alzheimer's disease,AD)是一种中枢神经系统原发性退行性变性疾病,临床主要表现为进行性记忆、理解、判断、定向等认知功能障碍,精神行为异常以及生活能力减退。 |
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Advance on Reason of Occuring on AD;
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老年性痴呆病发病机理的研究近况 |
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Discussion on pathogenesis of senile dementia from the point of Zangfu-organs theory;
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老年性痴呆的中医理论探讨 |
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Analysis of drug law of compound prescription in treating Alzheimer disease;
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老年性痴呆复方用药规律探讨 |
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Comparative study of clinical features and magnetic resonance imaging results between Alzheimer disease and vascular Dementia;
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老年性痴呆与血管性痴呆临床MRI对比研究 |
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Elderly hemeatogenous disseminated pulmonary tuberculosis:a clinical analysis of 30 cases;
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老年血行播散型肺结核30例临床分析 |
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Study on renin-angiontensin Ⅱ-aldosterone in the elderly depression;
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老年抑郁症血浆肾素、血管紧张素Ⅱ与醛固酮研究 |
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Anti-inflammatory and analgesic effects of triptolide loaded in microemulsion-based gel;
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雷公藤内酯微乳凝胶抗炎镇痛作用的实验研究 |
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Effect of ramiprili on Fas/Apo-1 in patients with congestive heart failure;
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雷米普利对充血性心力衰竭患者Fas/Apo-1水平的影响 |
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Effect of combined regimen of Rapamycin and Cyclosporine on renal transplant recipients;
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雷帕霉素联合环孢霉素A在肾移植受者中的应用 |