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BPAGs which are located at the lamina lucida and hemidesmosome in BMZ are produced and secreted by the basal cells in the epidermis, including the main antigen BP 0 and the minor antigen BP80 which are critically important to the BP pathogenesis. |
中文意思: 大疱性类天疱疮抗原(bullous pemphigoid antigen,BPAG),由表皮基底细胞产生,分布于基底膜的透明层、半桥粒处。 其主要抗原为BPAG(BP 0),位于基底细胞内半桥粒附着斑处,为高分子量( 0KD)的多肽。 |
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