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cyclization

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英文: Diazaspiro [4.4] nonane was synthesized from malononitrile as the starting material by a series of nucleleophilic displacement, hydrolytic cyclization and carbonyl reduction.

中文: 摘要以丙二腈爲原料,经过亲核取代、水解环合、羰基还原系列反应,合成了2,7-二氮螺[4.4]壬烷。        更详细...
英文: Hydroxyquinol triacetate was prepared from p-benzoquinone by 1,4-addition reaction with acetic anhydride and then 6,7-dihydroxy coumarin was synthesized from it by hydrolyze and cyclization in concentrated sulfuric acid.Then 6,7-dimethoxy coumarin was syn

中文: 对苯醌与乙酸酐经1,4-加成生成1,2,4-苯三酚三乙酸酯,然后与苹果酸反应经水解、环合反应得6,7-二羟基香豆素,再经甲基化得到6,7-二甲氧基香豆素,总收率为74.4%,整个过程反应条件温和,操作方便,适合工业生产的要求,对产品结构进行了IR和1HNMR表征。        更详细...
英文: Methods Pinocembrin and its derivatives were synthesized with 2,4,6-trihydroxy-phenylethanone as the starting material via four steps including protection of the hydroxy-group, condensation, cyclization and deprotection.

中文: 方法以2,4,6-三羟基苯乙酮为起始原料,经羟基保护、缩合、环化、脱保护合成目标化合物。        更详细...
英文: Mirtazapine was prepared by a seven-step reaction, namely nucleophilic ring-opening reaction, chlorination, cyclization, uncleophilic substitution, hydrolysis, reduction and cyclization from styrene oxide and N-methylethanolamine as the starting materials

中文: 摘要以环氧苯乙烯和N-甲基乙醇胺为起始原料,经亲核开环、氯代和环合反应得到中间体1-甲基-3-苯基哌嗪。        更详细...
英文: The paper introduces a new highly-effective synthesis method. Decoquinate was synthesized with catechol as starting materials via substitution, reduction, and at last cyclization with Dowtherm Aas solvent.

中文: 摘要以邻苯二酚为原料,通过一系列取代反应,再经过还原、缩合,最后在高沸点的混合有机溶剂中关环。制备的3-喹啉羧酸乙酯衍生物的总收率为24.2%。        更详细...
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