以下为句子列表：
英文: Focus on the bioinformatics analysis of DNA methylation.
中文: 主要研究DNA甲基化的生物信息学分析。
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英文: The main changes in epigenetic status such as DNA methylation,histone modification, and chromosome remodeling were discussed briefly in this paper.
中文: 本文扼要地讨论了几种主要的表观遗传改变如DNA甲基化、组蛋白修饰和染色质重塑等改变,以及伴随或促进非遗传毒性致癌物引起的致癌过程及其作用机理;对化学致癌物引起的表观遗传改变可以在代间相传这一新发现作了简要介绍;并提出了今后值得关注的问题。
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英文: Epigenetic modification includes DNA methylation and histone modifications.
中文: 表观遗传修饰主要有DNA甲基化和以组蛋白修饰为特征的染色质重塑。
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英文: Aberrant methylation may be the most common mechanism of inactivating cancer-related genes in lung cancer, and histone modification may be closely associated with DNA methylation.
中文: 表遗传学机制在肺癌的形成中占据重要地位,包括DNA的甲基化和组蛋白修饰,肺癌中与癌形成有关基因的失活多与异常甲基化有关,并且组蛋白修饰和甲基化紧密联系着。
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英文: Although the importance of genetic mutations and deletion in cancer have long been recognized,the role of epigenetic modification including DNA methylation and histone modification has been suggested more recently.
中文: 肿瘤的形成受遗传学修饰和表观遗传修饰的影响。
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