详细解释：
| By exploring the key enzymes of several probable antibiotic biosynthesis pathways in the identified proteins of strain 103, only polyketide synthase and other proteins associated with the polyketide pathways were found, indicating that Maituolaimysin might be synthesized through the polyketide pathway. |
| 运用生物信息学手段,结合实验室研究结果,将所有可能的代谢途径关键酶在所构建的数据库中进行搜索,两个菌株中均发现有聚酮合成途径的关键酶聚酮合成酶和其它几个与该途径相关的酶,说明麦拓莱霉素通过聚酮合成途径合成。 |
| In polyketide synthase, thioesterase (TE) domain was responsible for release and cyclization of polyketide chain, so it was important to polyketide biosynthesis. |
| 在聚酮合成酶(polyketide synthase，PKS)中，硫酯酶(thioesterase，TE)负责将聚酮长链从PKS上水解下来，并在其它酶域的协助下环化为大环内酯环，因此对聚酮的生物合成非常重要。 |
| In type I polyketide synthase,thioesterase domain was responsible for release and cyclization of polyketide chain. |
| 在I型聚酮合成酶(polyketide synthase,PKS)中,硫酯酶结构域(Th ioesterase,TE)负责将聚酮长链从PKS上水解下来,并协助环化为大环内酯环。 |
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