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Abstract: 1-(4-Pyridinyl)-2-propanone,which is the key intermediate of synthesizing the milrinone ,a cardiotonic agent,was synthesized from 4-methyl-pyridine by acetylation in dichloromethane and phase transition catalyzing hydrolysis.The overall yield wa
中文意思:
文摘:报道了以4-甲基吡啶为原料,经酰化和相转移催化水解反应制备强心药物米利酮关键中间体1-(4-吡啶基)-2-丙酮的新合成方法,总收率达73.1%.


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